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Functional Gastrointestinal Disorders (FGIDs)


The Rome Foundation provides a definition and classification system (Rome IV criteria) for FGIDs which is based on evidence-based review.

A. Esophageal Disorders

A1. Functional chest pain
A2. Functional heartburn
A3. Reflux hypersensitivity
A4. Globus
A5. Functional dysphagia

B. Gastroduodenal Disorders

B1. Functional dyspepsia
B1a. Postprandial distress syndrome (PDS)
B1b. Epigastric pain syndrome (EPS)

B2. Belching disorders
B2a. Excessive supragastric belching
B2b. Excessive gastric belching

B3. Nausea and vomiting disorders
B3a. Chronic nausea vomiting syndrome (CNVS)
B3b. Cyclic vomiting syndrome (CVS)
B3c. Cannabinoid hyperemesis syndrome (CHS)

B4. Rumination syndrome

C. Bowel Disorders

C1. Irritable bowel syndrome (IBS)
C1a. IBS with predominant constipation (IBS-C)
C1b. IBS with predominant diarrhea (IBS-D)
C1c. IBS with mixed bowel habits (IBS-M)
C1d. IBS unclassified (IBS-U)

C2. Functional constipation
C3. Functional diarrhea
C4. Functional abdominal bloating/distension
C5. Unspecified functional bowel disorder
C6. Opioid-induced constipation

D. Centrally Mediated Disorders of Gastrointestinal Pain

D1. Centrally mediated abdominal pain syndrome (CAPS)
D2. Narcotic bowel syndrome (NBS)/Opioid-induced GI hyperalgesia

E. Gallbladder and Sphincter of Oddi (SO) Disorder

E1. Biliary pain
E1a. Functional gallbladder disorder
E1b. Functional biliary SO disorder

E2. Functional pancreatic SO disorder

F. Anorectal Disorders

F1. Fecal incontinence

F2. Functional anorectal pain
F2a. Levator ani syndrome
F2b. Unspecified functional anorectal pain
F2c. Proctalgia fugax

F3. Functional defecation disorders
F3a. Inadequate defecatory propulsion
F3b. Dyssynergic defecation


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